Literaturverzeichnis


Literaturverzeichnis von Arbeiten, die unter Beteiligung des Vereins bzw. in Kooperation des Institutes für Klinische Neuroimmunologie und der Marianne-Strauß- Klinik erschienen sind:

Farina C, Then Bergh F, Albrecht H, Meinl E, Yassouridis A, Neuhaus ,; Hohlfeld R.Treatment of multiple sclerosis with Copaxone (COP): Elispot assay detects COP-induced interleukin-4 and interferon-gamma response in blood cells Brain 2001 Apr;124(Pt 4):705-19

M.S. Weber, M. Starck, S. Wagenpfeil,  E. Meinl, R. Hohlfeld, C. Farina. Multiple sclerosis: Glatiramer Acetate inhibits monocyte reactivity in vitro and in vivo. BRAIN 2004, 127:1370-1378

M. Krumbholz, D. Theil, T. Derfuss, A. Rosenwald, F. Schrader, C-M Monoranu, S.L. Kalled, D.M. Hess, B. Serafini, F. Aloisi, H. Wekerle, R. Hohlfeld, E. Meinl. BAFF is produced by astrocytes and up-regulated in multiple sclerosis lesions and primary central nervous system lymphoma. J. Exp. Med. 2005, 201:195-200.

T Derfuss, R. Hohlfeld, E. Meinl. Intrathecal antibody (IgG) production against human herpesvirus type 6 occurs in about 20 % of multiple sclerosis patients and might be linked to a polyspecific B-cell
response. J.Neurol. 2005, 252:968-971

C. Farina, M. Weber, E. Meinl, H. Wekerle, R. Hohlfeld. Glatiramer acetate (GLAT) in multiple sclerosis: Update on potential mechanism(s) of action. Lancet Neurology 2005, 4:567-575

M. Krumbholz, D. Theil, S. Cepok, B. Hemmer, P. Kivisakk, R. M. Ransohoff, M. Hofbauer, C. Farina, T. Derfuss, C. Hartle, J. Newcombe, R. Hohlfeld, E. Meinl. Chemokines in MS: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment. Brain 2006, 129:200-211

E. Meinl, M. Krumbholz, R. Hohlfeld. B lineage cells in the inflammatory CNS environment: Migration, maintenance, local antibody production, and therapeutic modulation. Ann.Neurol. 2006, 59:880-892

C. Farina, F. Aloisi, E. Meinl. Astrocytes are active players in cerebral innate immunity Trends. Immunol. 2007, 28:138-145

L-A Hoffmann , M. Krumbholz, H. Faber, T. Kümpfel, M. Starck, W. Pöllmann, E. Meinl, R. Hohlfeld. Multiple sclerosis: Relating MxA transcription to anti-interferon-beta neutralizing antibodies. Neurology 2007, 68:958-959

R. Hohlfeld, M. Kerschensteiner, E. Meinl. Dual role of inflammation in CNS disease. Neurology 2007, S58-63

E.K. Mathey*, T. Derfuss*, M.K. Storch, K.R. Williams, K. Hales, D.R. Woolley, A. Al-Hayani, S.N. Davies, M. Rasband, T. Olsson, A. Moldenhauer, S. Velhin, R. Hohlfeld, E. Meinl*, C. Linington*. Neurofascin as a novel target for autoantibody-mediated axonal injury. * equal contribution.  J.Exp.Med. 2007, 204:2363-2372

M. Krumbholz, D. Theil, F. Steinmeyer, S. Cepok, B. Hemmer, M. Hofbauer, C. Farina, T. Derfuss, A. Junker, T. Arzberger, I. Sinicina, C. Hartle, J. Newcombe, R. Hohlfeld, and E. Meinl CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions J.Neuroimmunol. 2007, 190:72-79

Kümpfel T, Hoffmann LA, Pöllmann W, Rieckmann P, Zettl UK, Kühnbach R, Borasio GD, Voltz R.Palliative care in patients with severe multiple sclerosis : two case reports and a survey among German MS neurologists. Palliat Med 2007 Mar; 21(2): 109-114

Kümpfel T, Hoffmann LA, Rübsamen H, Pöllmann W, Feneberg W, Hohlfeld R, Lohse P.Late-onset tumor necrosis factor receptor-associated periodic syndrome in multiple sclerosis patients carrying the TNFRSF1A R92Q mutation. Arthritits Rheum 2007 Aug; 56(8):2774-2783

M. Krumbholz*, H. Faber*, F. Steinmeyer, L.A. Hoffmann, T. Kümpfel, H. Pellkofer, T. Derfuss, C. Ionescu, M. Starck, C. Hafner, R. Hohlfeld, and E. Meinl. Interferon- increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity. * equal contribution. Brain 2008, 131:1455-1463

Hoffmann LA, Lohse P, König FB, Feneberg W, Hohlfeld R, Kümpfel T.TNFRSF1A R92Q mutation in association with a multiple sclerosis-like demyelinating syndrome. Neurology 2008 Mar 25; 70(13 Pt 2):1155-1156

M. Krumbholz, I. Meinl, T. Kümpfel, R. Hohlfeld, E. Meinl. Natalizumab disproportionately increases circulating pre-B and B cells in multiple sclerosis. Neurology 2008, 71:1350-1354

Kümpfel T, Hoffmann LA, Pellkofer H, Pöllmann W, Feneberg W, Hohlfeld R, Lohse P.Multiple sclerosis and the TNFRSF1A R92Q mutation : clinical characteristics of 21 cases. Neurology 2008; 71:1812-1820

R. Hohlfeld, E. Meinl, K. Dornmair K B- and T-cell responses in multiple sclerosis: Novel approaches offer new insights. J.Neurol.Sci. 2008, 274:5-8

E. Meinl, M. Krumbholz, T. Derfuss, A. Junker, R. Hohlfeld. Compartmentalization of inflammation in the CNS: a major mechanism driving progressive multiple sclerosis. J.Neurol.Sci. 2008, 274:42-44

T Derfuss, K Parikh, S Velhin, M Braun, E Mathey, M Krumbholz, T Kümpfel, A Moldenhauer, C Rader, P Sonderegger, W Pöllmann, C Tiefenthaller, J Bauer, H Lassmann, H Wekerle, D Karagogeos, R Hohlfeld, C Linington*, E Meinl*. Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals. Proc Natl Acad Sci USA 2009, 106:8302-8307

A Junker, M Krumbholz, S Eisele, H Mohan, F Augstein, R Bittner, H Lassmann, H Wekerle, R Hohlfeld, E Meinl. MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47. Brain 2009, 132:3342-3352

H Mohan, M Krumbholz, R Sharma, S Eisele, A Junker, M Sixt, J Newcombe, H Wekerle, R Hohlfeld, H Lassmann, E Meinl. Extracellular Matrix in Multiple Sclerosis Lesions: Fibrillar Collagens, Biglycan and Decorin are Upregulated and Associated with Infiltrating Immune Cells. Brain Pathol. 2010, 20:966-975

Axo-glial antigens as targets in multiple sclerosis: implications for axonal and grey matter injury. T Derfuss, C Linington, R Hohlfeld, E Meinl. J Mol Med. 2010, 88:753-761

Humoral autoimmunity in multiple sclerosis. Meinl E, Derfuss T, Krumbholz M, Pröbstel AK, Hohlfeld R. J Neurol Sci. 2010 Sep 2.
Emerging role of miRNAs in multiple sclerosis. Junker,A., R.Hohlfeld, and E.Meinl. 2011. Nat.Rev.Neurol 2011, 7:56-59

Bareyre FM, Garzorz N, Lang C, Misgeld T, Bünning H & Kerschensteiner M. In vivo imaging reveals a phase-specific role of STAT3 during CNS and PNS axon regeneration. Proc Natl Acad Sci U S A. 2011 108:6282-7

Nikic I, Merkler D, Sorbara C, Brinkoetter M, Kreutzfeld M, Bareyre FM, Brück W, Bishop D, Misgeld T (*) & Kerschensteiner M (*). (*co-senior authors) A reversible form of axon damage in multiple sclerosis and its animal model. Nat Med. 2011, 17:495-9
            
Misgeld T(*), Kerschensteiner M (*), Bareyre FM, Burgess RW & Lichtman JW.  Imaging axonal transport of mitochondria in vivo. Nature Methods 2007; 4(7): 559-61(* co-first authors)